6ORY3HGLDWU
Prikaz primera / Case report
3,7<5,$6,69(56,&2/2535,26(0/(71(0'(ý.8±
35,.$=35,0(5$
3,7<5,$6,69(56,&2/25,1$1±<($52/'%2<±
CASE REPORT
27RþNRYDï0.UVWLüð06WDUEHN=RUNRï
'HUPDWRYHQHURORãNDNOLQLND8QLYHU]LWHWQLNOLQLþQLFHQWHU/MXEOMDQD/MXEOMDQD6ORYHQLMD
=GUDYVWYHQLGRPâNRIMD/RNDâNRIMD/RND6ORYHQLMD
,=9/(ý(.
3LW\ULDVLVYHUVLFRORUMHJOLYLþQDEROH]HQSRYUKQMLKSODVWLNRåHNDWHUHSRY]URþLWHOMLVRNYDVRYNHL]URGXMa- ODVVH]LDVSHF6SHVWULPLNOLQLþQLPLVLPSWRPLVHSRMDYOMDSUHGYVHPQDNRåL]JRUQMHJDGHODWUXSDSULPODMãLK RGUDVOLK9RWURãNLGRELMHEROH]HQUHGND=DSRVWDYLWHYGLDJQR]HVWDSRPHPEQLDQDPQH]DLQNOLQLþQDVOLND SRWUGLPRSDMR]GRGDWQLPODERUDWRULMVNLPGLDJQRVWLFLUDQMHP9SULVSHYNXSUHGVWDYOMDPRSULPHURVHPOH- WQHJDGHþND]UHGNRL]ROLUDQRREOLNRSLW\ULDVLVYHUVLFRORUQDNRåLREUD]D
.OMXþQHEHVHGHSLW\ULDVLVYHUVLFRORURWURNGLDJQRVWLFLUDQMH]GUDYOMHQMH
ABSTRACT
3LW\ULDVLVYHUVLFRORULVDFRPPRQEHQLJQFKURQLFVXSHU¿FLDOIXQJDOLQIHFWLRQRIWKHVNLQFDXVHGE\WKH K\SKDO¿ODPHQWRXVIRUPRI 0DODVVH]LDVSS7KHRFFXUUHQFHRI39EHIRUHSXEHUW\RUDIWHUWKHDJHRI
\HDUVLVXQFRPPRQ7KHLQYROYHGVNLQUHJLRQVDUHXVXDOO\WKHWUXQNWKHEDFNDQGWKHSUR[LPDOH[WUHPLWLHV ,VRODWHGIDFLDOLQYROYHPHQWLVUDUH7KHGLDJQRVLVEDVHGRQFOLQLFDOSUHVHQWDWLRQVKRXOGEHFRQ¿UPHGE\
SRWDVVLXPK\GUR[LGH.2+H[DPLQDWLRQ:HSUHVHQWDFDVHRIDQ\HDUROGSUHYLRXVO\KHDOWK\ER\ZLWK UDUHSUHVHQWDWLRQRI39LQIHFWLRQ
.H\ZRUGVSLW\ULDVLVYHUVLFRORUFKLOGUHQGLDJQRVWLFVWUHDWPHQW
892'
3LW\ULDVLVYHUVLFRORU39MHNURQLþQDEODJDLQQDYD- GQRDVLPSWRPDWVNDJOLYLþQDEROH]HQSRYUKQMHSODVWL HSLGHUPLVD3RY]URþDMRMRNYDVRYNHL]URGXMalas- VH]LD VSHF 3LW\URVSRUXP QDMSRJRVWHMHMalasse- ]LDIXUIXU in 0DODVVH]LDJORERVD±9VDSUR¿WQL nemicelijski obliki so lahko omenjene kvasovke GHOQRUPDOQHPLNURÀRUHNRåH=DSUHKRGYSDWRJH- QRPLFHOLMVNRREOLNRLQSRMDYEROH]QLMHSRWUHEHQ YSOLYUD]OLþQLKSUHGLVSR]LFLMVNLKGHMDYQLNRY39 VH]DþQHSRMDYOMDWLYSXEHUWHWLYUKREROHYQRVWLSDMH SULPODMãLKRGUDVOLK3ULRWURFLKLQVWDUHMših ljudeh MH EROH]HQ UHGNDPri odraslih se bolezenski znaki YHþLQRPDSRMDYOMDMRQDNRåL]JRUQMHJDGHODWUXSD UDPHQLKYUDWXLQ]JRUQMLKGHOLKURN6SUHPHPEHQD NRåLREUD]DVRUHGNHLQQHQDYDGQHWHUYQDVSURWMX ] RGUDVOLPL SRJRVWHMãH SUHG SXEHUWHWR ± =D EROH]HQVR]QDþLOQHSHVWUDNOLQLþQDVOLNDLQSRJRVWH SRQRYLWYH
35,.$=35,0(5$
3UHGVWDYOMDPRSULPHURVHPOHWQHJDGHþNDNLMH]D- UDGLVXPDQDYLWLOLJRRELVNDOQDãRDPEXODQWR3RUR- þDOMHRGYDWHGQDWUDMDMRþLKDVLPSWRPDWVNLKEHOLK OLVDKNLVRVHVSUYDSRMDYLOHQDNRåLþHODRGNRGHU so se dokaj hitro razširile na zgornjo polovico obra- ]D6OLND'HþHNMHELOVLFHU]GUDYLQEUH]]QDQLK EROH]QLUHGQHJD]GUDYOMHQMDLQ]QDQLKDOHUJLM7HåDY VNRåRGRWHGDMQLLPHOSUDYWDNRYGUXåLQLQLKþHQL LPHOSRGREQLKNRåQLKVSUHPHPE
2ESUHJOHGXVRELOHSRNRåLþHODVãLUMHQMHPQDSH- ULRNXODUQLGHOLQ]JRUQMRSRORYLFRNRåHQRVXLQOLFD vidne okrogle, dokaj ostro omejene in drobno lu- ãþHþHVHKLSRSLJPHQWLUDQHPDNXOHNLVRVH]OLYDOH YYHþMHDUHDOH1DRVWDOLNRåLQLVPRXJRWDYOMDOLSR- GREQLKEROH]HQVNLKVSUHPHPE9VSORãQHPNOLQLþ- QHPVWDWXVXQLELORSRVHEQRVWL
2E]QDþLOQLNOLQLþQLVOLNLLQVXPXQDJOLYLþQRRNXå- ERNRåHVPRRSUDYLOLQDWLYQLPLNURVNRSVNLSUHJOHG
VNDUL¿NDWDREROHOHNRåHNLMHSRND]DONUDWNHãLURNH in fragmentirane hife ter skupke velikih spor, pod :RRGRYRVYHWLONRSDVRSUL]DGHWDPHVWDREUD]DÀXR- UHVFLUDOD]HOHQNDVWRUXPHQR3RVWDYLOLVPRGLDJQR]R 39 WHU JOHGH QD GRNWULQDUQD SULSRURþLOD VYHWRYDOL YHþWHGHQVNRORNDOQR]GUDYOMHQMH]LPLGD]ROQLPDQ- WLPLNRWLNRPYNRPELQDFLML]XVWUH]QLPSURWLJOLYLþ- QLP ãDPSRQRP =D SUHSUHþLWHY SRQRYLWYH EROH]QL VPRSULSRURþLOLY]GUåHYDOQRYHþPHVHþQR]GUDYOMH- QMH]DQWLPLNRWLþQLPãDPSRQRPSUHGYVHPY]DþHW- NX SROHWMD 5HSLJPHQWDFLMR KLSRSLJPHQLUDQLK OLVVPRNOMXEXVWUH]QHP]GUDYOMHQMXSULþDNRYDOLãHOH v naslednjih mesecih, kar smo pojasnili tudi bolni- NRYLPVWDUãHP
3ULSRURþHQHJD SRQRYQHJD RELVND GHUPDWRORãNH DPEXODQWH]DUDGLY]WUDMDQMDDOLSRQDYOMDQMDNRåQLK VLPSWRPRYGHþHNYQDVOHGQMLKGYHKOHWLKQLSRWUH- ERYDO3UHGNUDWNLPVRSULEROQLNXXJRWRYLOLDWRSLMR in diagnosticirali bronhialno astmo
EPIDEMIOLOGIJA
39MHUD]širjena po vsem svetu, predvsem v tropskih SRGURþMLKVWRSORLQYODåQRNOLPRNMHUSULQHNDWH- ULKSRSXODFLMDKGRVHJDNDUPHGWHPNRMHY 6NDQGLQDYLMLUD]ãLUMHQRVWVDPR%ROH]HQVH pojavlja neodvisno od rase in spola ter predvsem pri
6OLND3LW\ULDVLVYHUVLFRORUQDNRåLREUD]D
)LJXUH3LW\ULDVLVYHUVLFRORURQWKHIDFLDOVNLQRIWKHIDFH
PODMãLKRGUDVOLKQDMSRJRVWHMHPHGLQOHWRP VWDURVWLNRVRåOH]HORMQLFHQDMEROMDNWLYQH3R OHWXVWDURVWLLQYRWURãWYXVHEROH]HQSRMDYOMDUHGNR SULRWURFLKMHSRMDYQRVWSULEOLåQR±
ETIOLOGIJA
1DMSRJRVWHMHL]ROLUDQLL]PHGãWHYLOQLKYUVWOLR¿OQLK kvasovk sta 0DODVVH]LDIXUIXU in 0DODVVH]LDJORER- sa±=DSUHKRGJOLYHYSDWRJHQRREOLNRLQSR- MDYEROH]QLMHQXMQDSULVRWQRVWUD]OLþQLKGHMDYQLNRY SUHGYVHPYODåQHJDRNROMD1DSRMDYEROH]QLYSOL- vajo med drugim izdatno znojenje, topiþQa uporaba UD]OLþQLKROMQLKSULSUDYNRYWHUMHPDQMHNRUWLNRVWH- roidov in kontracepcijskih zdravil pa tudi pridru- åHQHEROH]QLQSU&XVKLQJRYDEROH]HQEROQLNRYR LPXQVNRVWDQMHLQSUHKUDQMHQRVWL±%ROH]HQ ni nalezljiva in ni povezana s higienskimi navada- PL . SRMDYX EROH]QL YHUMHWQR SRPHPE . SRMDYX EROH]QL YHUMHWQR SRPHPE . SRMDYX EROH]QL YHUMHWQR SRPHPE- no vpliva tudi genetska nagnjenost, saj pri pribli- åQREROQLNRYXJRWDYOMDPREROH]HQYGUXåLQL 3ULVRWQRVWOLSR¿OQLKNYDVRYNMHSULRWURFLK in mladostnikih z atopijo enaka kot pri vrstnikih brez znane atopije, vendar pri bolnikih z atopijskim GHUPDWLWLVRP XJRWDYOMDMR SULVRWQRVW SURWLWHOHV ,J(
SURWLSRY]URþLWHOMX3LW\URVSRUXP
Patogeneza bolezni ni v celoti pojasnjena, najverje- tneje pa igrajo pomembno vlogo dejavniki, kot so SRWHQMH VSUHPHPEH Y VHVWDYL NRåQLK OLSLGRY SUHG puberteto in po njej ter tudi spremembe v sestavi DPLQRNLVOLQLQGHSR]LWD]XQDMFHOLþQHJDJOLNRJHQDY SUL]DGHWLNRåL7RYUVWQDGRJDMDQMDJRYRULMR Y SULG KLSRWH]L GD 39 QL OH SRVOHGLFD UD]UDãþDQMD JOLYYSRYUãLQVNHPGHOXHSLGHUPLVD
./,1,ý1$6/,.$
=D EROH]HQ VR ]QDþLOQH YHþLQRPD DVLPSWRPDWVNH DOL UDKOR VUEHþH LQ RVWUR RPHMHQH RYDOQH GR RNUR- JOHPDNXOHNLVHSRJRVWRPHGVHERM]GUXåXMHMRY YHþMH QHSUDYLOQR REOLNRYDQH OLVH NL VH SRMDYOMDMR
na zgornjem delu trupa, ramenih, vratu in proksi- PDOQLKGHOLK]JRUQMLKXGRY.RåQHVSUHPHPEHVR ODKNRUD]OLþQLKEDUYQLKRGWHQNRYRGWRGSRLPHQR- vanje versicolor9YHþLQLYLGLPRGUREQROXãþHþD VH åDULãþD URåQDWRUMDYNDVWH EDUYH YDULDWLR IXVFD ODKNRSDVHSRMDYLMRKLSRSLJPHQWLUDQDåDULãþDva- ULDWLR DOED NL VR SRVOHGLFD LQKLELWRUQHJD YSOLYD D]HODLQVNHNLVOLQHNYDVRYNHQDWLUR]LQD]R
%ROH]HQVHODKNRNDåHWXGL]DVLPSWRPDWVNLPLSD- SXODPL 3UL LPXQVNR RVODEHOLK EROQLNLK RSL- VXMHMR LQYHU]QR UD]OLþLFR 39 NL SUL]DGHQH L]ROLUD- QHGHOHNRåHREUD]DLQXGRYWHUSUHJLEH,]ROLUDQH VSUHPHPEHQDNRåLREUD]DVRVLFHU]HORUHGNHDSUL RWURFLKEROMSRJRVWHNRWSULRGUDVOLK3R3R3R3R3R- URþDMRWXGLRSUL]DGHWRVWLQHQDYDGQLKGHORYWHOHVD NRWVRVSRORYLODYHNHDUHROHGODQLLQSRGSODWL
DIAGNOSTICIRANJE
3RVWDYLWHYGLDJQR]HWHPHOMLQDDQDPQH]LLQNOLQLþQL sliki, za potrditev pa moramo opraviti tudi mikolo- ãNL SUHJOHG 3UDYLORPD ]DGRãþD QDWLYQL PLNRORãNL SUHJOHG RVWUXåNRY ] YLGQLPL NUDWNLPL ãLURNLPL LQ fragmentiranimi hifami ter skupki velikih spor z ]QDþLOQR VOLNR»špagetov z mesnimi kroglicami«
.YDVRYNH L] URGXMalassezia absorbirajo dolgo- YDORYQR XOWUDYLMROLþQR VYHWORER LQ MR RGVHYDMR NRW YLGQR ÀXRUHVFHQFR 3UL WUHWMLQL EROQLNRY SUL]DGHWD SRGURþMDSRG:RRGRYRVYHWLONRÀXRUHVFLUDMRUGHþ- NDVWRDOL]HOHQNDVWRUXPHQRNDUMHYSRPRþSULSR- VWDYLWYLSUDYLOQHGLDJQR]H9QHMDVQLKSULPHULK VHL]MHPRPDRGORþLPRWXGL]DKLVWRORãNRGLDJQRVWL- FLUDQMH
DIFERENCIALNA DIAGNOZA
+LSRSLJPHQWLUDQHOLVHYVNORSX39YDULDWLRDOED YþDVLK VDPR QD SRGODJL NOLQLþQH VOLNH WHåNR UD]OL- NXMHPRRGGHSLJPHQWLUDQLKåDULãþ]QDþLOQLK]DYL- tiligo, lahko pa jih zamenjamo tudi za hipopigmen- WLUDQDåDULãþDEROH]QLSLW\ULDVLVDOEDNLMH]QDþLOQD
NRåQDVSUHPHPEDSULEROQLNLK]DWRSLMR9þDVLKQD 39VSRPLQMDMRWXGLUH]LGXDOQHKLSRSLJPHQWDFLMHNL QDVWDQHMRSRR]GUDYLWYLRVQRYQHGHUPDWR]HOXVND- YLFDHNFHPLDOLGUXJDYQHWMDGLDJQRVWLþQLSUREOHP pa je lahko tudi hipopigmentirana oblika fungoidne PLNR]H
39YDULDWLRIXVFDODKNRSRVQHPDUD]OLþQHNRåQH VSUHPHPEHNRWVRSLW\ULDVLVURVHDVHERURLþQLGHU- PDWLWLV GHUPDWR¿WLMD DOL NRQÀXHQWQD UHWLNXODUQD SDSLORPDWR]D2ESUL]DGHWRVWLQHQDYDGQLKGHORYWH- OHVDSUHJLELMRPRUDPRUD]OLNRYDWLRGNDQGLGRPL- FHWLþQHJD YQHWMD LQYHU]QH OXVNDYLFH DOL HULWUD]PH ob prisotnosti sprememb na dlaneh ali podplatih pa PRUDPRSRPLVOLWLWXGLQDVHNXQGDUQLVL¿OLV
.OMXþQHJDSRPHQD]DSRVWDYLWHYSUDYLOQHGLDJQR]H LQXVSHãQR]GUDYOMHQMHVRQDWDQþQDRVHEQDGUXåLQ- ska in epidemiološka anamneza ter ustrezno labora- WRULMVNRGLDJQRVWLFLUDQMH
ZDRAVLJENJE
3ULEROQLNLKV39MH]GUDYOMHQMHL]ELUHORNDOQR]GUD- YOMHQMH9YHþLQLSULPHURYVRXþLQNRYLWLLPLGD]ROVNL antimikotiki in lokalni alilamini v kremah, raztopi- QDKLQVXVSHQ]LMDKWHUWXGLSURWLJOLYLþQLãDPSRQL ,]VOHGNLUD]LVNDYNDåHMRGDVRORNDOQLDOLODPLQL ELVWYHQR PDQM XþLQNRYLWL NRW LPLGD]ROVNL DQWLPL- NRWLNL3UYLQDPUHþXVSHãQRL]NRUHQLQLMRJOLYLFHQD NRåLYPHGWHPNRGUXJLYNDU2EXSR- rabi šamponRY V VHOHQLMHYLP VXO¿GRP GRVHåHPR R]GUDYLWHY SUL VNRUDM EROQLNRY
medtem ko je uspešnost šampona s cinkovim piri- tionom ali zdravljenja z vodno suspenzijo propilen JOLNRODRGVWRWQD
=D VLVWHPVNR DOL NRPELQLUDQR DQWLPLNRWLþQR ]GUD- YOMHQMHVHRGORþLPROHSUL]HORUD]ãLUMHQLKREOLNDK bolezni, ob pogostih recidivih ali pri imunsko osla- EHOLKEROQLNLK,]VOHGNLUD]LVNDYJRYRULMRR SULEOLåQRHQDNLXþLQNRYLWRVWLREHKVLVWHPVNLKDQWL- PLNRWLNRY±LWUDNRQD]RODLQÀXNRQD]ROD3UHG
uvedbo sistemskega zdravljenja moramo diagnozo 39SRWUGLWLWXGLODERUDWRULMVNR.HUVHEROH]HQ SRJRVWRSRQDYOMDSULSRURþDPRY]GUåHYDOQRDOL SUR¿ODNWLþQR]GUDYOMHQMH
=$./-8ý(.
9 SULVSHYNX VPR SUHGVWDYLOL SULPHU RVHPOHWQHJD GHþNDNLVPRJDREUDYQDYDOLYQDãLDPEXODQWL]D- radi nenadno nastalih asimptomatskih, diskretno OXãþHþLKVHEHOLKOLVQDNRåL]JRUQMHSRORYLFHREUD- ]D=L]YLGRPQDWLYQHJDPLNURVNRSVNHJDSUHJOHGD VNDUL¿NDWDSUL]DGHWHNRåHLQSUHJOHGRP]:RRGRYR VYHWLONR VPR QD SRGODJL NOLQLþQH VOLNH SRVWDYOMHQ VXPQD39WXGLODERUDWRULMVNRSRWUGLOLýHSUDYODK- NRSRY]URþLWHOMDEROH]QLNYDVRYNHL]URGXMalla- sezia VSYVDSUR¿WQLREOLNLRVDPLPRWDNRQDNRåL GRMHQþNRYNRWWXGLQDNRåLRGUDVOLKVHEROH]HQSUHG SXEHUWHWRSRMDYL]HORUHGNR
1HRELþDMHQ þDV SRMDYD EROH]QL MH ODKNR ND]DOQLN SULVRWQRVWL UD]OLþQLK SULGUXåHQLK EROH]QL NRW VR imunska pomanjkljivost, podhranjenost ali endokri- QRORãNHQHSUDYLOQRVWL7HKSULQDãHPEROQLNXQLVPR potrdili kot tudi ne genetske nagnjenosti k nastanku EROH]QLVDMSRGDWNRYREROH]QLSULGUXJLKGUXåLQ- VNLK þODQLK QL ELOR .HU Y OLWHUDWXUL QH XJRWDYOMDMR VWDWLVWLþQRSRPHPEQRYHþMHJDãWHYLODOLSR¿OQLKNYD- sovk pri otrocih z atopijo, ugotovljena atopija pri našem bolnikov verjetno ni vzrok pojava bolezen- VNLK]QDNRY.OMXESRJRVWHMãLSULVRWQRVWLVSUHPHPE QDNRåLREUD]DSULRWURFLKVRL]ROLUDQHVSUHPHPEH QDNRåLREUD]DYRWURštvuUHGNHLQQHQDYDGQH Dejavnikov, ki bi lahko vplivali na pojav bolezni na QHQDYDGQLKPHVWLKãHQHSR]QDPR
39MHSULRWURFLKSUHGSXEHUWHWR]HORUHGNDDPRåQD
=DUDGL SHVWULK ]D EROH]HQ ]QDþLOQLK NOLQLþQLK ]QD- NRYPRUDPRRESRMDYXKLSRSLJPHQWLUDQLKSRGURþLM QD NRåL þHOD LQ REUD]D Y RWURãWYX YHGQR SRPLVOLWL WXGL QD PRåQRVW RPHQMHQH EROH]QL 6 SRVWDYLWYLMR pravilne diagnoze in uvedbo ustreznega zdravljenja ODKNRSULþDNXMHPRSRSROQXPLNNRåQLKVLPSWRPRY
/,7(5$785$
*XSWD$.%DWUD5%OXKP5)DHUJHPDQQ- 3LW\ULDVLVYHUVLFRORU'HUPDWRO&OLQ
&UHVSR(UFKLJD 9 )ORUHQFLR 9' 0DODVVH]LD
\HDVWV DQG SLW\ULDVLV YHUVLFRORU Curr Opin ,QIHFW'LV
*DLWDQLV*9HOHJUDNL$$OH[RSRXORV(&&KD- VDSL97VLJRQLD$.DWVDPEDV$'LVWULEXWLRQ of Malassezia species in pityriasis versicolor DQG VHERUUKRHLF GHUPDWLWLV LQ *UHHFH7\SLQJ RI WKH PDMRU SLW\ULDVLV YHUVLFRORU LVRODWH 0 JORERVD Br J Dermatol 0RULVKLWD 1 6HL < 6XJLWD 7 0ROHFXODU DQDO\VLV RI PDODVVH]LD PLFURÀRUD IURP SDWL- HQWVZLWKSLW\ULDVLVYHUVLFRORU Mycopatholo- gia
5LQFRQ6&HOLV$6RSR/0RWWD$&HSHURGH
*DUFLD0&0DODVVH]LD\HDVWVSHFLHVLVRODWHG IURPSDWLHQWVZLWKGHUPDWRORJLFOHVLRQV Bio- medica
.ULVDQW\5,%UDPRQR.0DGH:LVQX,,GHQ- WL¿FDWLRQ RI 0DODVVH]LD VSHFLHV IURP SLW\ULD- VLVYHUVLFRORULQ,QGRQHVLDDQGLWVUHODWLRQVKLS ZLWK FOLQLFDO FKDUDFWHULVWLFV Mycoses
'ROHQF9ROMþ 0 *OLYLþQH NRåQH EROH]QL 9 .DQVN\ $ 0LOMNRYLü - XU .RåQH LQ VSROQH EROH]QL /MXEOMDQD =GUXåHQMH GHU- PDWRYHQHURORJRYVWU
7HUUDJL//DVDJQL$2ULDQL$HWDO3LW\UL- DVLVYHUVLFRORULQWKHSHGULDWLFDJH3HGLDWU 'HUPDWRO
%RXDVVLGD6%RXGD\D6*KRUEHO5HWDO Pityriasis versicolor in chlildren: a retro- VSHFWLYHVWXG\RIFDVHV$QQ'HUPDWRO 9HQHUHRO
3RQWDVFK0-.\DQNR0(%URGHOO577L- nea vesricolor of the face in black children LQDWHPSHUDWHUHJLRQ&XWLV +HUVOH . 6HOHQLXP VXOSKLGH WUHDWPHQW RI WL- QHDYHUVLFRORU$FWD'HUP9HQHUHRO
*XSDWD$.%OXKP56XPPHUEHOO53LW\UL- DVLV YHUVLFRORU - (XU$FDG 'HUPDWRO9HQHURO
)DHUJHPDQQ-0DQDJHPHQWRIVHERUUKHLFGHU- PDWLWLV DQG SLW\ULDVLV YHUVLFRORU $P - &OLQ 'HUPDWRO
+DIH] 0 (O6KDP\ 6 *HQHWLF VXVFHSWLELOLW\
LQ SLW\ULDVLV YHUVLFRORU 'HUPDWRORJLFD
)DHUJHPDQQ-0DQDJHPHQWRIVHERUUKHLFGHU- PDWLWLV DQG SLW\ULDVLV YHUVLFRORU $P - &OLQ 'HUPDWRO
0HQGH]7RYDU /- 3DWKRJHQHVLV RI GHUPD- WRSK\WRVLVDQGWLQHDYHUVLFRORU&OLQ'HUPDWRO
*XSWD$.%OXKP56XPPHUEHOO53LW\ULD- VLV YHUVLFRORU - (XU$FDG 'HUPDWRO9HQHUHRO
6FKZDUW] 5$ 6XSHU¿FLDO IXQJDO LQIHFWL- RQV/DQFHW +DIH] 0 HO6KDP\ 6 *HQHWLF VXVFHSWLELOLW\
LQ SLW\ULDVLV YHUVLFRORU 'HUPDWRORJLFD
+H 60 'X :' <DQJ 6 HW DO 7KH JHQHWLF HSLGHPLRORJ\ RI WLQHD YHUVLFRORU LQ &KLQD 0\FRVHV
:HVVHOV0:'RHNHV*YDQ,HSHUHQYDQ.LMN
$*.RHUV:-<RXQJ(,J(DQWLERGLHVWR3L- W\URVSRUXPLQDWRSLFGHUPDWLWLV%U-'HUPDWRO
*ORRU0.XPSHO')LHGULFK+&3UHGLVSR- sing factors of the surface of the skin in per- VRQVZLWKSLW\ULDVLVYHUVLFRORU$UFK'HUPDWRO 5HV
.HGGL )0 $ QRYHO FHOOXODU UHDFWLRQ FDXVHG E\WLQHDYHUVLFRORU([WUDFHOOXODUJO\FRJHQGH- SRVLWV-,QYHVW'HUPDWRO *DODGDUL,HO.RP\00RXVD$HWDO7LQHD
versicolor: histologic and ultrastructural inve- VWLJDWLRQRISLJPHQWDU\FKDQJHV,QW-'HUPD- WRO
1D]]DUR3RUUR 0 3DVVL 6 ,GHQWL¿FDWLRQ RI tyrosinase inhibitos in cultures of Pityrospo- UXP-,QYHVW'HUPDWRO
6XZDWWHH 3 &KDP 30 6RORPRQ 5. .D\H 91 7LQHD YHUVLFRORU ZLWK LQWHUIDFH GHUPDWL- WLV J Cutan Pathol .DXU,+DQGD6.XPDU%7LQHDYHUVLFRORU
LQYROYHPHQW RI XQXVXDO VLWHV ,QW - 'HUPDWRO
+XDQJ::7KDUS 0'$ FDVH RI WLQHD YHU- VLFRORURIWKHH\HOLGV3HGLDWU'HUPDWRO H
'UDNH$'LQHKDUW60)DUPHU(U*ROW]5:
*UDKDP*)+RUGLQVN\0.HWDO*XLGHOLQHV RIFDUHIRUVXSHU¿FLDOP\FRWLFLQIHFWLRQVRIWKH VNLQ 3LW\ULDVLV WLQHD YHUVLFRORU JXLGHOLQHV 2XWFRPHV&RPPLWWHH$PHULFDQ$FDGHP\RI 'HUPDWRORJ\-$P$FDG'HUPDWRO
+X6:%LJE\03LW\ULDVLVYHUVLFRORUDV\VWH- PDWLFUHYLHZRILQWHUYHQWLRQV$UFK'HUPDWRO
+XOO &$ -RKQVRQ 60$ GRXEOHEOLQG FRP- parative study of sodium sulfacetamide lotion YHUVXVVHOHQLXPVXO¿GHORWLRQLQWKH WUHDWPHQWRISLW\ULDVLVWLQHDYHUVLFRORU&XWLV
)UHGULNVVRQ 7 )DHUJHPDQQ - 'RXEOHEOLQG comparison of a zinc pyrithione shampoo and its shampoo base in the treatment of tinea ver- VLFRORU&XWLV
)DHUJHPDQQ-)UHGULNVVRQ73URS\OHQHJO\FRO LQWKHWUHDWPHQWRIWLQHDYHUVLFRORU$FWD'HUP 9HQHUHRO
6DQGKX . .DQZDU $- ([WHQVLYH SLW\ULDVLV YHUVLFRORURIWKHIDFH-'HUPDWRO
.RQWDNWQDRVHED&RQWDFWSHUVRQ 2OJD7RþNRYDGUPHG
Otroški oddelek
Dermatovenerološka klinika
8QLYHU]LWHWQLNOLQLþQLFHQWHU/MXEOMDQD
=DORãNDFHVWD 6,/MXEOMDQD
3ULVSHOR5HFHLYHG 6SUHMHWR$FFHSWHG
